This book has been written keeping in mind the technological advancements in the field of health care and the services that are demanded by the critical care staff nurses, who indeed one of the front line caregivers in the critical care units. In this rapidly changing world, there are many challenges for a critical care nurse as the needs, expectations of the society are increasing, and the nursing care is moved towards the family-oriented model from the traditional patient-oriented model. A prudent critical care nurse needs to be competent in taking care of the patients. As a vital member of the health care team, the nurse is expected to be responsible and accountable for the outcome of the patient under her/his care. One of the areas of competency expected by a critical care nurse is ECG monitoring and interpretation, which will help the critical care nurses in clinical decision making and responding diligently to the unstable health conditions of the patients. Melita Sheilini is currently an Assistant Professor – Selection Grade at Manipal College of Nursing, Manipal. She pursued her MSc Nursing degree in Cardiovascular and Thoracic Nursing specialty from Manipal College of Nursing Manipal, MU, Manipal. She has more than 10 years of experience in teaching undergraduate and postgraduate nursing students and has 18 national and international publications to her credit. She has actively involved as the instructor for the Basic Life Support programs conducted at Manipal University, Manipal. She has conducted Continuing Nursing Education classes on ECG monitoring and Interpretation for the staff nurses working at National as well as international levels.